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and Redux, both weight loss drugs that were once highly popular, worked by suppressing hunger urges in the brain by altering serotonin levels.During the 1990s, doctors began to prescribe these drugs in combination to increase the weight loss effect. Studies have demonstrated serious potential health risks associated with the use of these drugs. These findings were so serious that the Food and Drug Administration (FDA) withdrew Fen-Phen and Redux from the market in 1997.Problems associated with the use of these diet drugs include:* serious heart murmurs,* heart valve leaks,* thickening of the heart valves, and* heart valve regurgitation, which is a build-up of a plaque-like substance on the heart valves.A 1997 report from the Mayo Clinic found heart valve dysfunction in 30% of Fen-Phen users who were tested. Fen-Phen also… Continue reading

The U.S. Food and Drug Administration (FDA) states its purpose in the following mission statement:"The FDA is responsible for protecting the public health by assuring the safety, efficacy, and security of human and veterinary drugs, biological products, medical devices, our nation's food supply, cosmetics, and products that emit radiation. The FDA is also responsible for advancing the public health by helping to speed innovations that make medicines and foods more effective, safer, and more affordable; and helping the public get the accurate, science-based information they need to use medicines and foods to improve their health."In 2005 the FDA provided a public draft guidance document to the pharmaceutical industry on the development of drugs to treat acne vulgaris, or acne. The draft guidance document contains the FDA's current thinking on the… Continue reading